Summary: Researchers produced a chromosome-scale genome for Agaricus subrufescens, assembling 13 chromosomes and annotating genes tied to metabolism and potential bioactive pathways. The dataset is a foundation for future work on biosynthesis (e.g., β-glucans/secondary metabolites), strain improvement, and functional studies—useful background for growers and ingredient standardization, but it does not make clinical claims.
Source: Research in Microbiology (DOI: 10.1016/j.resmic.2023.104116)
Citation: Abreu CG, Roesch LFW, Andreote FD, et al. Decoding the chromosome-scale genome of the nutrient-rich Agaricus subrufescens: a resource for fungal biology and biotechnology. Research in Microbiology. 2023;174(8):104116. doi:10.1016/j.resmic.2023.104116
Summary: Using Illumina and Nanopore sequencing, the authors assembled a chromosome-scale genome (13 chromosomes) for A. subrufescens, providing annotations relevant to metabolism and putative bioactive pathways. The resource enables downstream work on biosynthesis (e.g., β-glucans/secondary metabolites), strain improvement, and functional genomics.
- What’s new: Chromosome-scale assembly for a nutritionally/medically notable species.
- Why it matters: Supports discovery and standardization rather than making clinical claims.
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