Agaricus subrufescens (Agaricus Blazei, ABM)

Agaricus subrufescens (also known as Agaricus blazei, ABM, Himematsutake) is a culinary medicinal mushroom rich in β-glucans and other polysaccharides. In herbal and integrative practice it’s used primarily for immune modulationand general vitality support. Traditional preparations include strong hot-water decoctions (teas), powders/capsules, and dual extracts (hot water + alcohol) to capture both water-soluble polysaccharides and alcohol-soluble compounds.

How it’s used: Daily powder/capsule servings or long-simmered teas are typical; many clinicians prefer dual-extracted products standardized for β-glucan content and tested for contaminants (heavy metals, pesticides, microbial load).

What the science says: Preclinical and human studies show effects on innate and adaptive immune markers and antioxidant status. Clinical outcomes vary by product and dose; ABM is best positioned as an adjunctive, food-like support, not a stand-alone treatment.

Safety: Usually well tolerated. Avoid with mushroom allergy. Because ABM can modulate immune activity, use caution with autoimmune conditions, post-transplant status, or concurrent immunosuppressants. Discuss with a clinician if pregnant, nursing, or managing chronic conditions.